You're probably familiar with the term, "You can do anything you set your mind to." Humanity in general is capable of doing remarkable things, even outside of Christ. Nobody can deny that. We can set remarkable goals and achieve them: we can build businesses, architecture, create beautiful paintings and music, etc. All of these attributes come we being created in God's image, as we see we were in Genesis 1-2. All of humanity has been given an amazing creative attribute in many ways. Unfortunately, ever since Genesis 3, we have lived in a fallen world, and all of us are born into sin. While we may still have amazing creativity and and ingenuity, unless the Holy Spirit has opened our eye to Christ, and the Lord has enabled us to, we are incapable of setting our minds on the things of God. We may be able to make money, do wonderful things for humanity, build nations, and go to space, but fallen man is no longer capable of seeking God. Take a moment and read Romans 8:5-8 -
"For those who live according to the flesh set their minds on the things of the flesh, but those who live according to the Spirit set their minds on the Spirit. For to set the mind on the flesh is death, but to set the mind on the Spirit is life and peace. For the mind that is set on the flesh is hostile to God, for it does not submit to God's law; indeed, it cannot. Those who are in the flesh cannot please God."
Mark "successful" once you've let those verses sink in.